中国麻风皮肤病杂志 ›› 2018, Vol. 34 ›› Issue (10): 577-579，584.

• 论著 •    下一篇

浅层X线放射治疗基底细胞癌和鳞状细胞癌27例疗效分析

单晓峰，杨宝琦，田洪青，张福仁   

  1. 山东省皮肤病医院，济南，250022
  • 出版日期:2018-10-15 发布日期:2018-12-03
  • 通讯作者: 张福仁，E-mail: zhangfuren@hotmail.com

Efficacy of superficial X-ray in the treatment of 27 patients with basal and squamous cell carcinoma

SHAN Xiaofeng, YANG Baoqi, TIAN Hongqing, ZHANG Furen   

  1. Shandong Provincial Hospital for Skin Diseases, Jinan 250022, China
  • Online:2018-10-15 Published:2018-12-03
  • Contact: ZHANG Furen, E-mail: zhangfuren@hotmail.com

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摘要： 目的：评价浅层X射线治疗皮肤基底细胞癌（BCC）和鳞状细胞癌（SCC）的疗效。方法：回顾分析2014年6月至2017年7月在我院应用浅层X射线治疗的27例原发性BCC(14例)和SCC(13例)患者，所有患者均经过组织病理学确诊，因健康状况、年龄、皮损部位等原因不适用手术而选用浅层X线治疗。结果：27例患者的31处皮损均痊愈，受照总剂量为45.6-53.2 Gy，随访 2年 仅1例患者1处皮损复发。不良反应主要为放射性皮炎及皮损处的溃烂，皮损体积较大者多伴有疼痛，一般1个月内消失。结论：浅层X射线放射治疗SCC和BCC疗效好，复发率低，对因各种原因不适合手术治疗的患者，是较为理想的方法。

关键词: 浅层X线, 基底细胞癌, 鳞状细胞癌

Abstract: Objective: To assess the efficacy of superficial X-ray therapy in the treatment of?basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Methods: The data of 14 patients with BCC and 13 with SCC diagnosed by biopsy and treated with superficial X-ray therapy in our hospital from June 2014 to July 2017 was analyzed retrospectively. Results: Thirty one lesions in 27 patients were disappeared. The total X-ray dose was 45.6-53.2 Gy. There was only one lesion in one SCC patient relapsed after 2 years follow-up. The adverse effects were radiodermatitis and ulceration that usually disappeared in 1 month. Conclusions: Superficial X-ray treatment is effective and has low recurrence in the treatment for BCC and SCC, which is an option for the patient who are not suitable for surgical intervention.

Key words: superficial X-ray, basal cell carcinoma, squamous cell carcinoma