儿童色素减退型蕈样肉芽肿一例并文献复习

中国麻风皮肤病杂志 ›› 2018, Vol. 34 ›› Issue (11): 672-675.

儿童色素减退型蕈样肉芽肿一例并文献复习

王超¹赵振坤²许静¹狄正鸿¹

1中国医科大学附属盛京医院皮肤科，辽宁沈阳，110004 2中国医科大学附属盛京医院病理科，辽宁沈阳，110004

出版日期:2018-11-15 发布日期:2018-12-01
通讯作者: 狄正鸿，E-mail:dizh2005@163.com
基金资助:

Childhood hypopigmented mycosis fungoides: a case report and literature review

WANG Chao¹，ZHAO zhenkun²，XU Jing¹，DI Zhenghong¹

1.Department of Dermatology, Shengjing Hospital, China Medical University, Shenyang 110004, China; 2.Department of Pathology, Shengjing Hospital, China Medical University, Shenyang 110004, China

Online:2018-11-15 Published:2018-12-01
Contact: DI Zhenghong,E-mail:dizh2005@163.com

摘要/Abstract

摘要： 报告儿童色素减退型蕈样肉芽肿一例并对相关文献进行复习。患儿，男，7岁。周身皮肤出现色素减退斑、红斑结痂1年，无明显瘙痒。组织病理检查：角层轻度角化，表皮轻度增生，可见淋巴样细胞亲表皮现象，真皮内可见团块状样细胞浸润。免疫组化示：CD3(+);CD20(个别+)；CD21（-）；Ki-67（+10%）；CD2（+）；CD5（+）；CD7（+）；CD8（少许+）；CD4（+）。诊断：色素减退型蕈样肉芽肿。给予患儿NB-UVB治疗3个月皮损基本消退，目前维持治疗中。

关键词: 色素减退型蕈样肉芽肿, 儿童, 淋巴瘤

Abstract: A case of childhood hypopigmented mycosis fungoides was reported and literatures were reviewed. A 7-year-old boy presented with depigmentation all over the body and scattered erythemas for one year without pruritus. Skin biopsy revealed that the corneum keratinization and hyperplasia of epidermis slightly, lymphoido cyte epidermotropism, dermis lymphocytic infiltration in clusters. Immunohistochemistry revealed that the infiltrating cells were positive for CD3, CD20 (some), Ki-67（10%）, CD2, CD5, CD7, CD8（a few）, CD4 and negative for CD21. A diagnosis of childhood hypopigmented mycosis fungoides was made. The lesions were almost disappear after 3 months therapy of NB-UVB. The child is still under treatment.

Key words: hypopigmentation mycosis fungoides, child, lymphoma

中图分类号:

王超, 赵振坤, 许静, 狄正鸿. 儿童色素减退型蕈样肉芽肿一例并文献复习[J]. 中国麻风皮肤病杂志, 2018, 34(11): 672-675.

WANG Chao, ZHAO zhenkun, XU Jing, DI Zhenghong. Childhood hypopigmented mycosis fungoides: a case report and literature review [J]. China Journal of Leprosy and Skin Diseases, 2018, 34(11): 672-675.

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