中国麻风皮肤病杂志 ›› 2026, Vol. 42 ›› Issue (2): 92-96.doi: 10.12144/zgmfskin202602092

• 论著 • 上一篇    下一篇

2014-2024年山东省梅毒流行病学时空特征分析

范高远1,2,李珍1,2,暴芳芳1,2,初同胜1,2,黄娜1,2,郑荣涛1,2,侯建玲1,2,田洪青1,2,刘殿昌1,2,刘红1,2,张福仁1,2   

  1. 1山东第一医科大学附属皮肤病医院，山东济南，250022； 2山东省皮肤病性病防治研究所，山东济南，250022
  • 出版日期:2026-02-15 发布日期:2026-01-28

Spatiotemporal characteristics of syphilis epidemiology in Shandong Province, China (2014-2024)

FAN Gaoyuan1,2, LI Zhen1,2, BAO Fangfang1,2, CHU Tongsheng1,2, HUANG Na1,2, ZHENG Rongtao1,2, HOU Jianling1,2, TIAN Hongqing1,2, LIU Dianchang1,2, LIU Hong1,2, ZHANG Furen1,2   

  1. 1 Dermatology Hospital of Shandong First Medical University, Jinan 250022, China; 2 Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2026-02-15 Published:2026-01-28

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摘要： 目的：分析山东省梅毒流行病学特征，为预防和控制梅毒提供理论依据。方法：运用SPSS、Geoda和ArcGIS等工具，基于2014-2024年山东省梅毒数据对其时间、空间分布进行分析。结果：山东省梅毒总体发病率呈现上升趋势（EAPC=3.08，P＜0.01），其中隐性梅毒增长最快（EAPC=8.58，P＜0.01）。相较而言，一期、二期、三期及胎传梅毒发病率均呈不同程度下降，其中胎传阶段梅毒下降最明显（EAPC=-15.83，P＜0.01）。梅毒在全省呈现显著的空间聚集特征，且聚集格局随时间演变发生变化，高发区早期集中在东部沿海县/区，近年逐步向中部、西部内陆地区扩展。结论：山东省梅毒疫情呈现总体上升、隐性梅毒主导、高发区由东部向西部转移的多重特征。防控策略应当从“被动发现”向“主动筛查”转变，从“全省一体”向“重点聚焦”调整。

关键词: 梅毒, 流行特征, 时空分布

Abstract: Objective: To analyze the epidemiological characteristics of syphilis in Shandong Province from 2014 to 2024, providing a theoretical basis for prevention and control strategies. Methods: The temporal and spatial distribution characteristics of syphilis data in Shandong Province from 2014 to 2024 was analyzed in SPSS, Geoda and ArcGIS. Results: The reported incidence of syphilis showed an upward trend (EAPC=3.08, P＜0.01), with latent syphilis exhibiting the fastest growth (EAPC=8.58, P＜0.01). In comparison, the reported incidences of primary, secondary, tertiary and congenital syphilis declined to varying degrees, among which congenital syphilis demonstrated the most significant decrease (EAPC=-15.83, P＜0.01). Spatially, syphilis in Shandong exhibited significant clustering patterns and has changed over time, initially the high-incidence areas concentrated in eastern coastal counties/districts and have gradually expanded to central and western regions in recent years. Conclusion: The syphilis epidemic in Shandong Province presents multiple characteristics such as an overall increase, latent dominance, and the shift of high-incidence areas from east to west. Strategiesof syphilis prevention and control should be transformed from passive detection to active screening and a uniform provincial approach should be shifted to targeted interventions in key regions.

Key words: syphilis, epidemiological characteristics, spatiotemporal distribution