Abstract: Objective: To explore the prognostic factors of bullous pemphigoid (BP) and provide reference of clinical practice. Methods: The clinical data of 101 BP patients diagnosed from January 1, 2016 to September 30, 2019 in the Inpatient Department of Dermatology, Lanzhou University second hospital were retrospectively reviewed, and the prognostic factors were analyzed. Results: Of the 101 BP patients, 15 died within one year, and the one-year fatality rate was 16.30%. Univariate analysis showed that the related factors affecting the death of BP patients were advanced age, Karnofsky performance status (KPS) score ≤40 points, concomitant stroke, concomitant heart diseases. Multivariate analysis found that advanced age, KPS score ≤40 points, and concomitant stroke were independent risk factors for death in BP patients. Conclusion: The one-year fatality rate of BP patients was 16.30%. The poor prognostic factors affecting the fatality rate were advanced age, KPS score ≤40 points, and concomitant stroke.

Key words: bullous pemphigoid, prognosis, fatality rate