Abstract: Objective: To summarize the clinical features and treatment of the patients with psoriasis vulgaris complicated with bullous pemphigoid. Methods: The data of the patients diagnosed as psoriasis vulgaris complicated with bullous pemphigoid in our hospital from January 2016 to February 2018 was analyzed retrospectively. Results: Ten patients with psoriasis vulgaris with bullous pemphigoid were found, including 9 males and 1 female. The median age was (59.90±10.18) years. Psoriasis onset preceded bullous pemphigoid in all the patients. The bullous lesions occurred on the psoriatic lesions in 8 patients and bullous lesions occurred on the normal skin in 2. Nine patients were treated with corticosteroids and /or immunosuppressive agents, and one case was treated with tetracycline combined with niacinamide and narrow band UVB. After an follow-up of 150 to 1065 days, there was no new blister lesions occurred and psoriatic lesions remained stable in seven patients. Two cases were lost to follow-up and one died. Conclusion: Psoriasis vulgaris complicated with bullous pemphigoid was rare and mainly affects the elderly. Corticosteroids combined with immunosuppressants was effective for treating psoriasis vulgaris complicated with bullous pemphigoid. 

Key words: psoriasis, bullous pemphigoid, clinical analysis