China Journal of Leprosy and Skin Diseases ›› 2022, Vol. 38 ›› Issue (2): 110-111.doi: 10.12144/zgmfskin202202110

• Case Reports • Previous Articles     Next Articles

Acquired hemophilia associated with bullous pemphigus: a case report

CHE Xuanlin1,2,3,4, SU Juan1,2,3,4, CHEN Mingliang1,2,3,4   

  1. 1 Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008, China; 2 Hunan Key Laboratory of Skin Cancer and Psoriasis, Central South University, Changsha 410008, China; 3 Hunan Engineering Research Center of Skin Health and Disease, Central South University, Changsha 410008, China; 4 National Clinical Research Center for Geriatric Disorders (Xiangya Hospital), Changsha 410008, China
  • Online:2022-02-15 Published:2021-12-20
  • Contact: SU Juan, E-mail: sujuanderm@csu.edu.cn; CHEN Mingliang, E-mail: xymingliang@csu.edu.cn

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Abstract: The mortality rate of acquired hemophilia A (AHA) is 15%-42%, about 50% of AHA is idiopathic, and the other 50% is related to some underlying diseases, such as systemic lupus erythematosus, tumor, drug allergy, skin diseases (such as psoriasis, bullous pemphigoid) and so on. Herein, we report a patient with bullous pemphigoid complicated with AHA, who achieved significant efficacy after comprehensive treatment of oral prednisone and human prothrombin complex, cyclosporine.

Key words: bullous pemphigoid, acquired hemophilia, factor Ⅷ inhibitor