Abstract: Objective: To compare the differences in onychomycosis and the fungal stains between the psoriatics and non-psoriatics. Methods: Psoriatic patients and non-psoriatic patients were collected from December 2016 to April 2018. Direct microscopic examination with 20% KOH and culture were carried out in abnormal nails in all patients and both positivity of the two methods was regarded as the positive standard. Results: One hundred and ninety eight psoriatic patients and 168 non-psoriatic patients were collected. The positivity rates in psoriatic patients and non-psoriatic patients were 11.1% and 9.5%, with no significance difference (P=0.643). Fungal stains identification showed that dermatophytes accounted for 81.8% and yeasts accounted for 18.2% in psoriatic patients, while dermatophytes accounted for 93.7% and  yeasts accounted for 6.3% in non-psoriatic patients, with no significant differences (P>0.05) . Conclusion: There is no significant difference in onychomycosis and fungal stains between the psoriatic patients and non-psoriatic patients.

Key words: psoriasis, onychomycosis, prevalence