Abstract: We report the clinical characteristics and treatment of a case of systemic lupus erythematosus with diffuse non-scarring alopecia. On the basis of conventional treatment with glucocorticoids, hydroxychloroquine sulfate, and cyclophosphamide, the biological agent telitacept was successfully used. This case suggests that the traditional treatment combined with the biological agent telitacept treatment provides a new method and clinical experience for the treatment of lupus alopecia.

Key words: systemic lupus erythematosus, non cicatricial alopecia, telitacicept