SDF-1/CXCR4轴在皮肤及周围神经损伤修复中的研究进展

doi:10.12144/zgmfskin202404297

Abstract

Abstract: When the skin tissue is injured, its repair is crucial for restoring the stability of the skin. The chemokine factor SDF-1 plays a key role in this process. This paper provides a comprehensive review of the role of the SDF-1/CXCR4 axis in wound healing, neural repair at the site of injury, post-traumatic scar formation, and its impact on nerve pain at the injury site. The aim is to provide guidance for the development of more effective treatment methods and strategies for skin and peripheral nerve injuries.

Key words: skin repair, SDF-1/CXCR4 axis, bone marrow mesenchymal stem cells, peripheral nerve, scar

YOU Shuqiong, JIANG Fuqiong, WU Qian. Update of SDF-1/CXCR4 axis in skin and peripheral nerve injury repair[J].China Journal of Leprosy and Skin Diseases, 2024, 40(4): 297-300.

[1]	CHAI Ziyu, ZHANG Qi, LI Na, ZHANG Bin. Application of thinning flap from scar for repairing helix keloid [J]. China Journal of Leprosy and Skin Diseases, 2023, 39(4): 269-271.
[2]	Zulihumaer·Mosha, Buwajieer·Yakeya, LIU Jianyong, KANG Xiaojing. Malignant peripheral nerve sheath tumors with neurofibromatosis type 1: a case report [J]. China Journal of Leprosy and Skin Diseases, 2023, 39(4): 272-274.
[3]	CHEN Weiquan, ZHU Yao, ZHANG Ruining, WEI Rujing, CAI Chuanchuan. Expanding the horizons of clinical application of large spot size low fluence Q-switched 1064 nm Nd: YAG laser in dermatology [J]. China Journal of Leprosy and Skin Diseases, 2023, 39(1): 65-70.
[4]	SHI Bei, ZHAO Tao, LI Bing, WANG Junxia, WEI Jingyi, WANG Guan, GUO Weinan. Efficacy assessment of suction-curettage in the treatment of epidermal cyst complicated with infection [J]. China Journal of Leprosy and Skin Diseases, 2022, 38(11): 800-802.
[5]	HUA Sirui, WEN Pengfei, WANG Lin. A case of microcystic adnexal carcinoma misdiagnosed as scar for a long-time [J]. China Journal of Leprosy and Skin Diseases, 2021, 37(11): 725-726.
[6]	LI Man, WANG Fang, DING Xiaolan, DU Juan. Rosettes sign and spermatozoa-like structure under dermoscopy in a case with scar [J]. China Journal of Leprosy and Skin Diseases, 2020, 36(8): 486-487.
[7]	PENG Xi, XIONG Wei, HUANG Haiyan, ZOU Yanfen, JIANG Bin, LIU Xiaoming, JIAN Xingling, YU Bo. Effect of carbon dioxide fractional laser combined with pulsed dye laser on hypertrophic scar in rabbit ears [J]. China Journal of Leprosy and Skin Diseases, 2020, 36(5): 262-266.
[8]	ZHUANG Huadi, FENG Jie, LIU Shunying, ZENG Runxin, SONG Jinxuan, ZHAO Juhua. Meta analysis of efficacy and safety of platelet-rich plasma combined with fractional CO₂ laser treatment for atrophic acne scar [J]. China Journal of Leprosy and Skin Diseases, 2020, 36(2): 75-79.
[9]	CHEN Yanxuan, LIANG Jianfeng, WU Hanhui, QU Guoping, GUAN Jianying, WANG Haitang. Preliminary study on quantitative identification of keloid and hypertrophic scar by shear wave elastography [J]. China Journal of Leprosy and Skin Diseases, 2020, 36(2): 91-93.
[10]	ZHANG Jinling, YANG Wangen, XIE Jintang, XU Zheng. Analysis of disabilities among newly-detcted leprosy cases in Shaanxi Province [J]. China Journal of Leprosy and Skin Diseases, 2019, 35(4): 211-214.
[11]	SU Mingying, ZHU Yinghua. Clinical effect of ELectiric Light Synergy and erbium fractional laser for treating atrophic acne scar [J]. China Journal of Leprosy and Skin Diseases, 2019, 35(3): 155-157.
[12]	SHI Jianfei, CHEN Xiaodong. Effect of Shuxuetong injection on the expression of MMP-2 and ɑ-SMA in hypertrophic scars of rabbit ear [J]. China Journal of Leprosy and Skin Diseases, 2019, 35(1): 20-24.
[13]	WANG Yan, DONG Wei, ZHANG Hui. Assessment of 1565 nm non-ablative fractional laser combined with glucocorticoid injection in the treatment of hypertrophic scar [J]. China Journal of Leprosy and Skin Diseases, 2019, 35(1): 31-33.
[14]	ZHOU Bingni, LIU Huaxu. Update of laser treatment for pathological scars [J]. China Journal of Leprosy and Skin Diseases, 2018, 34(11): 701-704.
[15]	CHEN Xiaohua, YANG Rongde. Update of peripheral nerve lesion and imageology in leprosy [J]. China Journal of Leprosy and Skin Diseases, 2018, 34(10): 637-640.

Update of SDF-1/CXCR4 axis in skin and peripheral nerve injury repair

PDF (PC)

Like

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Metrics

Comments

Recommended 10