Abstract: The characteristics of large spot size low fluence Q-switched 1064 nm Nd: YAG laser(LF 1064nm QSNYL) are infrared wavelength, short pulse width, large spot and low energy. In recent years, it has been found that laser can not only treat pigmentary diseases, but also cause a series of non-thermal skin damage biological events, namely photobiomodulation. To provide available evidence to support clinicians to use on LF 1064 nm QSNYL-based therapies for treatment of multiple pigmentary disorders, skin rejuvenation, impairment of skin barrier, acne, hyperplastic scar, keloids and other dermatosis, this paper reviewed the extended application of LF 1064nm QSNYL in dermatology.

Key words: Q-switched 1064 nm Nd: YAG laser, low-fluence, photobiomodulation, acne, scar, skin rejuvenation