Abstract: Objective: To assess the clinical efficacy and safety of Danggui Kushen pills combined with blue and red light and tretinoin cream in the treatment of patients with moderate acne. Methods: One hundred and eighteen patients were randomly divided into two groups. Sixty patients in the treatment group were treated with Danggui Kushen pills combined with blue and red light and tretinoin cream for 4 weeks. Those in the control group were treated by blue and red light combined with tretinoin cream. The efficacy was assessed in the end of the treatment. Results: The effective rate of the treatment group and control group was 81.60% and 55.17% respectively, with significant difference (P＜0.05). Conclusion: Danggui kushen pills combined with blue and red light and tretinoin cream is effective and safe in the treatment of moderate acne.

Key words: Danggui Kushen pills, Blue and red light, tretinoin cream, acne