Abstract: Objective: To analyze the causative drugs in 239 inpatients with drug eruptions. Methods: Data of inpatients suffered from drug eruptions from May 2007 to April 2017 in our department were analyzed retrospectively. Results: Out of 239 patients, the allergenic drugs in 105 patients were identified, including 88 patients with severe drug eruption and 17 patients with non-severe drug eruption. The allergenic drugs in the patients with non-severe drug eruptions mainly included antibiotics in 32 patients (36.4%), antipyretic analgesics in 17 (19.3%) and traditional Chinese medicine in 16 (18.2%). The allergenic drugs in the patients with severe drug eruptions mainly included antibiotics in 5 patients (29.4%), antipyretic analgesics in 3 (17.6%) carbamazepine in 3 (17.6%) and antigout drugs in 3 (17.6%). Conclusion: The most allergenic drugs are antibiotics in this study.

Key words: drug eruption, clinical analysis, incubation period, retrospective analysis