苦参素联合抗组胺药治疗慢性荨麻疹疗效的Meta分析

Abstract

Abstract:

Objective: To assess the efficacy of the oxymatrine combined with antihistamines in the treatment of chronic urticaria. Methods: The articles about the oxymatrine combined with antihistamines for treating chronic urticaria were searched in CNKI, WANGFANG database, VIP database, Pubmed, EMbase and Cochrane library. The Meta-analysis was performed by Review Manager 4.2 software. Results: A total of 14 researches were included, with small bias and no heterogeneous (P=0.25). The results of meta-analyses showed that compared with the group of antihistamines alone, the effective rate in the group of oxymatrine combined with antihistamines was higher (P<0.00001,RR=1.40, 95% CI（1.30～1.51）) and the recurrence rate was lower (P<0.00001, RR=0.19，95% CI（0.10-0.37）). Conclusion: Oxymatrine combined with antihistamines was more effective than antihistamines alone in the treatment of chronic urticaria.

Key words: oxymatrine')">

oxymatrine, antihistamines, chronic urticarial, meta-analysis

XU Xueqin, LIU Xiaohui, SUN Chunyang, WANG Jinjin, PEI Lanying, MA Xiaomei, LIU Ying, YANG Mengli, YAN Guoli.

Meta-analysis of the efficacy of the oxymatrine combined with antihistamines in the treatment of chronic urticaria [J].China Journal of Leprosy and Skin Diseases, 2017, 33(4): 216-219.

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Meta-analysis of the efficacy of the oxymatrine combined with antihistamines in the treatment of chronic urticaria

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