Abstract: Objective: To assess the efficacy and safety of carbon assisted Q-switched 1064 nm Nd:YAG laser in the treatment of the patients with moderate-severe acne. Methods: One hundred and sixty-six patients with moderate-severe acne were divided into the experimental group (83 cases) and the control group (83 cases). All the patients were treated with minocycline capsules 100 mg twice a day and topical clindamycin Hydrochloride and meteonidazole liniment, three times a day. The patients in the experiment group were treated with additional carbon assisted Q-switched 1064 nm Nd:YAG laser, once every 10 days. Results: The effective rate in the experiment group was 87.76%, which was significantly higher than that in the control group (65.31%), with a significant difference (P<0.05). There was no obvious adverse reaction in all patients. Conclusion: Carbon assisted Q-switched 1064 nm Nd:YAG laser can enhance the therapeutic efficacy of drugs in the treatment of the patients with moderate-severe acne.

Key words: Nd:YAG laser, acne, carbon lotion