China Journal of Leprosy and Skin Diseases ›› 2026, Vol. 42 ›› Issue (7): 524-526.doi: 10.12144/zgmfskin202607524

• Case Reports • Previous Articles     Next Articles

Eosinophilic granulomatosis with polyangiitis presenting with initial skin lesions: a case report

ZHANG Yuanbin, LI Jinghuan, AI Dongfang, FENG Shijun   

  1. Department of Dermatology, Cangzhou Central Hospital, Hebei Medical University, Cangzhou 061000, China
  • Online:2026-07-15 Published:2026-06-29

Abstract: Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic necrotizing vasculitis with highly heterogeneous clinical manifestations, and only about 14% of patients present with skin lesions as the initial symptom. This paper reports a case of EGPA with skin lesions as the initial manifestation and positive anti-glomerular basement membrane (anti-GBM) antibodies.

Key words: eosinophilic granulomatosis with polyangiitis, skin onset, purpura, eosinophil, anti-GBM antibody