China Journal of Leprosy and Skin Diseases ›› 2018, Vol. 34 ›› Issue (11): 698-700,704.

Previous Articles     Next Articles

Update of tumor necrosis factor inhibitor for the treatment of non-psoriatic skin diseases

罗玲玲, 崔盘根   

  1. Institute of Dermatology,Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042, China
  • Online:2018-11-15 Published:2018-12-02
  • Contact: CUI Pangen, E-mail: cuipangen@126.com

Abstract: Inhibition of tumor necrosis factor (TNF) plays an important role in anti-inflammation through blocking the binding of TNF and receptors to suppressing the activation of inflammatory factors, transmission of intracellular signals and cell proliferation. The common TNF inhibitors including infliximab (IFX), etanercept (ENT) and adalimumab (ADA) have widely being used in the treatment of non-psoriatic skin diseases, which is reviewed in this paper.

Key words: tumor necrosis factor, inhibitor, skin diseases besides psoriasis