中国麻风皮肤病杂志 ›› 2019, Vol. 35 ›› Issue (7): 394-397.doi: 10.12144/zgmfskin201907394

• 论著 • 上一篇    下一篇

深圳市男男性接触人群梅毒合并HIV感染状况及其危险因素分析

吴秋红  陈威英  丁一  赵晴  陈文慧  虞兰兰  程紫昭  袁军  罗珍胄   

  1. 深圳市南山区慢性病防治院,深圳,518000
  • 出版日期:2019-07-15 发布日期:2019-07-11
  • 通讯作者: 罗珍胄,E-mail:paulluo9909@163.com

Co-infection of syphilis and HIV and risk factors among men who have sex with men in Shenzhen

WU Qiuhong, CHEN Weiying, DING Yi, ZHAO Qing, CHEN Wenhui, YU Lanlan, CHENG Zizhao,  YUAN Jun, LUO Zhenzhou   

  1. Shenzhen Nanshan District Chronic Disease Control Center, Shenzhen 518000, China
  • Online:2019-07-15 Published:2019-07-11
  • Contact: LUO Zhenzhou,E-mail:paulluo9909@163.com

摘要: 目的:了解深圳市近6个月内发生过同性临时性行为的MSM人群梅毒合并HIV感染状况及其相关影响因素。方法:运用滚雪球法和同伴推动抽样法招募MSM进行问卷调查和血清学检测,采用χ2检验和Logistic回归分析梅毒HIV合并感染的相关影响因素。结果:共调查434例MSM,梅毒和HIV感染率分别为16.4%和12.2%,梅毒合并HIV感染率为7.3%。年龄越大(OR=4.0,P=0.0007)、高中/中专文化者(OR=6.5,P=0.0081)、性角色以被动方为主者(OR=12.1,P=0.0017)、多个同性肛交性伴者(OR=1.5,P=0.0455)、不能坚持每次使用安全套者(OR=2.9,P=0.0236),其梅毒合并HIV感染风险越高。结论:需要采取更大努力来应对该人群的梅毒和HIV双重感染问题。

关键词: 男男性接触者, 人类免疫缺陷病毒, 梅毒

Abstract: Objective: To understand the co-infection of syphilis and human immunodeficiency virus (HIV) and the risk factors among men who have sex with men (MSM) (who had temporary anal sex in the last 6 months) in Shenzhen. Methods: The samples were collected by snowball and respondent-driven sampling method. Chi-square test and multivariate logistic regression model were used to analyze the factors associated with co-infection of syphilis and HIV. Results: A total of 434 MSM were investigated. The infection rates of syphilis, HIV and co-infection of syphilis-HIV were 16.4%, 12.2%, and 7.3%, respectively. Multivariate logistic regression analysis showed that the older MSM (OR=4.0, P=0.0007), senior middle school level (OR=6.5, P=0.0081), playing exclusively receptive roles in anal sexual intercourse (OR=12.1, P=0.0017), having more anal sexual partners (OR=1.5, P=0.0455) and not always using condom in anal sexual intercourse in the past 6 months (OR=2.9, P=0.0236) were associated risk factors for syphilis and HIV co-infection. Conclusion: More efforts are needed to deal with the high co-infection of syilhilis and HIV in this population. 

Key words: Men who have sex with men, human immunodeficiency virus, syphilis