中国麻风皮肤病杂志 ›› 2022, Vol. 38 ›› Issue (11): 810-811.doi: 10.12144/zgmfskin202211810

• 病例报告 • 上一篇    下一篇

面部结节性二期梅毒疹一例

周星雨*,冯叶*,梁愉笳,李亚萍   

  1. 中南大学湘雅二医院皮肤科，湖南长沙，410011
  • 出版日期:2022-11-15 发布日期:2022-10-25

Secondary syphilis in face with nodular lesions: a case report

ZHOU Xingyu*, FENG Ye*, LIANG Yujia, LI Yaping   

  1. Department of Dermatology, The Second Xiangya Hospital, Central South University, Changsha 410011, China
  • Online:2022-11-15 Published:2022-10-25

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摘要： 患者，男，20岁。头面部红色结节1个月。皮肤科检查：鼻周、口周淡红色结节，大小不一，部分结节有融合，表面呈疣状增生并覆盖黄色脓痂。实验室检查：TPPA阳性、RPR阳性（滴度1∶8）。组织病理检查：角质层及表皮内见大量中性粒细胞移入，真皮内间质及血管周围见大量浆细胞、淋巴细胞、组织细胞伴散在嗜酸粒细胞浸润。诊断为二期梅毒疹。经苄星青霉素治疗后，皮损基本消退。

关键词: 梅毒, 二期梅毒疹, 结节性二期梅毒

Abstract: A 20-year-old male presented with red nodules on the his face for one month. Dermatological examination: red nodules with different sizes can be seen on the face around the nose and the mouth. Some of the nodules are fused with verrucous hyperplasia and covered with yellow pus scabs. Laboratory examination: TPPA positive, RPR positive (titer 1∶8). Histological examination showed that a large number of neutrophils migrated into the stratum corneum and epidermis. And a large number of plasma cells, lymphocytes and histiocytes accompanied with scattered eosinophil infiltration were seen in the dermis. The final diagnosis is secondary syphilis. After treatment with benzylpenicillin, the lesions disappeared.

Key words: syphilis, secondary syphilis, nodular secondary syphilis