中国麻风皮肤病杂志 ›› 2019, Vol. 35 ›› Issue (10): 637-640.doi: 10.12144/zgmfskin201910637

• 综述 • 上一篇    下一篇

梅毒血清固定的产生及临床转归

刘焕颜1，2  梁晓冬2  邓婕1，2  叶瑞贤2  熊绮颖2  张锡宝2   

  1. 1广东医科大学，湛江，524023
    2广州市皮肤病防治所，广州，510095
  • 出版日期:2019-10-15 发布日期:2019-10-11
  • 通讯作者: 张锡宝，E-mail：zxibao@126.com

Occurrence and clinical outcome of syphilis serofast state

LIU Huanyan1,2, LIANG Xiaodong2, DENG Jie1,2, YE Ruixian2, XIONG Qiying2, ZHANG Xibao2   

  1. 1. Guangdong Medical University, Zhanjiang 524023, China; 2. Guangzhou Institute of Dermatology, Guangzhou 510095, China
  • Online:2019-10-15 Published:2019-10-11
  • Contact: ZHANG Xibao, E-mail：zxibao@126.com

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摘要： 梅毒血清固定产生机制及相关因素均尚不明确，且临床上具有较高的发生率。目前认为可能与年龄、RPR滴度、无症状神经梅毒、吉-海反应、梅毒螺旋体亚型、细胞免疫紊乱相关。梅毒血清固定是梅毒复发及多系统受累的危险因素。本文就梅毒血清固定的产生和临床转归方面进行综述。

关键词: 梅毒, 血清固定, 血清反应素滴度

Abstract: The mechanism of syphilis serofast and related factors are still unclear. Clinically, there is a high incidence of syphilis serofast. The phenomenon may be related to age, RPR titers, asymptomatic neurosyphilis, jarisch herxheimer reaction, Treponema pallidum subtype and cellular immune dysfunction. Syphilis serofast is a risk factor for syphilis recurrence and multiple system involvement. The occurrence and clinical outcome of syphilis serofast were reviewed in this article. 

Key words: syphilis, serofast, serum reactants titers