中国麻风皮肤病杂志 ›› 2023, Vol. 39 ›› Issue (4): 261-264.doi: 10.12144/zgmfskin202304261

• 临床研究 • 上一篇    下一篇

光动力联合CO2点阵激光治疗播散型扁平疣三例

陈晓萱1，2,付希安2,岳振华2,李建可2,刘红2,张福仁1，2   

  1. 1山东大学，山东济南，250012；
    2山东第一医科大学附属皮肤病医院（山东省皮肤病医院），山东省皮肤病性病防治研究所，山东济南，250022
  • 出版日期:2023-04-15 发布日期:2023-03-27

Three cases of disseminated flat warts treated successfully by photodynamic therapy combined with CO2 fractional laser

CHEN Xiaoxuan1,2, FU Xi'an2, YUE Zhenhua2, LI Jianke2, LIU Hong2, ZHANG Furen1,2   

  1. 1 Shandong University, Jinan 250012, China;
    2 Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250022, China
  • Online:2023-04-15 Published:2023-03-27

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摘要： 报道3例光动力联合CO2点阵激光治疗播散型扁平疣病例并回顾相关文献。例1头面部、躯干、四肢泛发皮疹5年。例2、3头面部多发丘疹，病程均大于2年。结合临床表现及皮肤镜诊断为：扁平疣（播散型）。予以光动力联合CO2点阵激光治疗,治疗2~3次，3位患者皮损完全清除,随访未见复发，未出现严重不良反应。回顾相关文献，扁平疣患者在光动力疗法前进行点阵激光预处理，治疗有效率可达96.4%。此效果确切、不良反应轻微的联合疗法为治疗播散型扁平疣提供了借鉴。

关键词: 播散型扁平疣, 光动力, CO2点阵激光

Abstract: We reported 3 cases of disseminated flat warts treated with photodynamic therapy combined with CO2 fractional laser and reviewed related literature. Case 1 had generalized rash on the head, face, trunk, and limbs lasting for 5 years. Case 2 and 3 had multiple papules on the head and face for more than 2 years. The diagnosis of disseminated flat warts was made according clinical manifestations and dermoscopy. After 2-3 treatments of photodynamic combined with CO2 fractional laser, the skin lesions of 3 patients were completely cleared, without serious adverse reactions and recurrence after follow-up. It showed that the treatment efficiency of fractional laser pretreatment before photodynamic therapy for flat wart was 96.4% by reviewing the literature. This combination therapy with exact effect and mild adverse reactions provided a reference for the treatment of disseminated flat warts.

Key words: disseminated flat wart, photodynamic therapy, CO2 fractional laser