中国麻风皮肤病杂志 ›› 2025, Vol. 41 ›› Issue (8): 549-551.doi: 10.12144/zgmfskin202508549

• 新发与再发感染性皮肤病 • 上一篇    下一篇

洋葱伯克霍尔德菌合并近平滑念珠菌皮肤感染一例

唐康恒,刘丽,王宇琪,丁小洁   

  1. 川北医学院附属医院皮肤科，四川南充，637000
  • 出版日期:2025-08-15 发布日期:2025-07-31

Skin infection caused by Burkholderia cepacia and Candida parapsilosis: a case report

TANG Kangheng, LIU Li, WANG Yuqi, DING Xiaojie   

  1. Department of Dermatology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China
  • Online:2025-08-15 Published:2025-07-31

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摘要： 洋葱伯克霍尔德菌合并其他致病菌导致健康成年人发生皮肤感染非常罕见，本文报道一例。患者，女，78岁，5个月前干农活时左手背受伤，后出现红斑、肿胀及结节，未正规治疗，结节渐扩大、增多。组织病理提示感染性肉芽肿。病原微生物宏基因组DNA检测提示洋葱伯克霍尔德菌和近平滑念珠菌。给予口服伊曲康唑、盐酸莫西沙星，外用聚维酮碘溶液治疗，1个月后皮损明显好转。

关键词: 皮肤感染, 结节, 洋葱伯克霍尔德菌, 近平滑念珠菌

Abstract: Skin infection caused by Burkholderia cepacia and other pathogenic bacteria is very rare in healthy adults. A 78-year-old female was injured on the back of her left hand 5 months ago. Then the lesion started to show erythema, swelling, and nodules. Pathological examination showed infectious granuloma. The metagenomic DNA detection of pathogenic microorganism suggests Burkholderia cepacia and Candida parapsilosis. The patient was treated with oral itraconazole, moxifloxacin hydrochloride, and topical povidone iodine solution. After one month of treatment, the skin lesions were significantly improved.

Key words: skin infection, nodules, Burkholderia cepacia, Candida parapsilosis