中国麻风皮肤病杂志 ›› 2016, Vol. 32 ›› Issue (3): 189-191.

• 综述 • 上一篇    

白癜风氧化应激发病机制的研究进展

赵晓菲 刘国艳   

  1. 潍坊医学院，潍坊，261000
  • 出版日期:2016-03-15 发布日期:2018-12-19
  • 通讯作者: 刘国艳，Email：wfliuguoyan@126.com
  • 基金资助:
    山东省自然基金(ZR2013HL068)，潍坊医学院附属医院科技创新基金项目(K12CX1009)

Update of the oxidative stress in the pathogenesis of vitiligo

ZHAO Xiaofei, LIU Guoyan   

  1. Weifang Medical College，Weifang，Shandong 261000, China
  • Online:2016-03-15 Published:2018-12-19
  • Contact: LIU Guoyan, E-mail: wfliuguoyan@126.com

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摘要： 白癜风发病机制复杂，涉及遗传、免疫、氧化应激、功能性黑素细胞凋亡和（或）丢失、神经体液等假说。本文将对Keap1/Nrf2/ARE信号转导通路与氧化应激进行综述。

关键词: 白癜风, 氧化应激, Keap1/Nrf2/ARE信号通路

Abstract: Pathogenesis of vitiligo is complex, involving genetic, immunity, oxidative stress, apoptosis of functional melanocytes and (or) loss and neurohormonal hypothesis, etc. Keap1/Nrf2/ARE pathway associated with oxidative stress was reviewed in this paper.

Key words: vitiligo, oxidative stress, Keap1/Nrf2/ARE signal pathway