中国麻风皮肤病杂志 ›› 2016, Vol. 32 ›› Issue (6): 379-381.

• 临床护理 • 上一篇    下一篇

机械应力对皮肤细胞生物学特性的影响

谭芹 彭琬苏 谭城   

  1. 南京中医药大学附属医院皮肤科,南京,210029
  • 出版日期:2016-06-15 发布日期:2018-12-27

Influences of mechanical stress on the pathophysiology of cutaneous cells

TAN Qin, PENG Wansu, TAN Cheng.   

  1. Department of Dermatology, Affiliated Hospital of Nanjing University of TCM, Nanjing, 210029, China
  • Online:2016-06-15 Published:2018-12-27

摘要: 皮肤含角质形成细胞、真皮成纤维细胞、黑素细胞等,机械应力作用可影响细胞形态、增殖、分化、迁移、内分泌等。该作用受机械应力种类、大小及时间长短和效应细胞所处细胞外基质等微环境的影响。机械应力作用影响皮肤伤口愈合、疤痕增生、色素沉着等一系列生理病理过程。

关键词: 机械应力, 角质形成细胞, 皮肤成纤维细胞, 黑素细胞

Abstract: Skin contains keratinocytes, fibroblasts and melanocytes. Mechanical stress can damage the proliferation, differentiation, migration, cellular morphology and endocrinology of the skin cells. The mechanical stress is affected by the species, magnitude of force, the length of time and the microenvironment of skin cells. The physiological and pathological process of healing of skin wound, scar and hyperpigmentation were also affected by mechanical stress.

Key words: mechanical stress, keratinocyte, dermal fibroblast, melanocyte