China Journal of Leprosy and Skin Diseases ›› 2019, Vol. 35 ›› Issue (10): 637-640.doi: 10.12144/zgmfskin201910637

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Occurrence and clinical outcome of syphilis serofast state

LIU Huanyan1,2, LIANG Xiaodong2, DENG Jie1,2, YE Ruixian2, XIONG Qiying2, ZHANG Xibao2   

  1. 1. Guangdong Medical University, Zhanjiang 524023, China; 2. Guangzhou Institute of Dermatology, Guangzhou 510095, China
  • Online:2019-10-15 Published:2019-10-11
  • Contact: ZHANG Xibao, E-mail:zxibao@126.com

Abstract: The mechanism of syphilis serofast and related factors are still unclear. Clinically, there is a high incidence of syphilis serofast. The phenomenon may be related to age, RPR titers, asymptomatic neurosyphilis, jarisch herxheimer reaction, Treponema pallidum subtype and cellular immune dysfunction. Syphilis serofast is a risk factor for syphilis recurrence and multiple system involvement. The occurrence and clinical outcome of syphilis serofast were reviewed in this article. 

Key words: syphilis, serofast, serum reactants titers