Abstract: Objective: To evaluate the implementation effect of the syphilis prevention and control program in Shandong Province, and to provide the basis for formulating the “14th Five-Year Plan of Syphilis Prevention and Control”. Methods: (1) The deployment, guidance, quality control and training of evaluation was carried out through top-down approach. (2) Basic data was collected by multi-department cooperation according to the division of labor. (3) The situation of safeguard measures, accuracy verification and awareness rate of STI knowledge among different groups were obtained through special investigation. The qualified rate of professional and technical personnel's knowledge mastery was obtained through the on-site examination of the APP XieShouYifang. (4) Self-evaluation, audit, check and accept of the program were performed through bottom-up approach. Results:  Among the 16 evaluation indicators, 13 met and 3 basically met the targets at the provincial level. The reported incidence of syphilis increased slowly since 2014, with an annual growth rate of 2.15%. The reported incidence of primary and secondary syphilis increased from 2010 to 2014, and decreased after 2014. The reported incidence of tertiary syphilis remained at a low level, although showed a slow upward trend. The reported incidence of congenital syphilis increased rapidly before 2012 and decreased rapidly after 2012. The reported incidence of latent syphilis showed an increasing trend, but the growth rate slowed down. Conclusion: The implementation of the syphilis prevention and control program in Shandong Province has achieved remarkable results. The prevalence of syphilis in Shandong Province is at a low level, and the increasing trend has been effectively curbed.

Key words: syphilis, program, evaluation