Abstract: Objective: To analyze the epidemiological features of leprosy cases newly detected in Guangxi from 2010 to 2020. Methods: The incidence data of leprosy in Guangxi from 2010 to 2020 were collected from Leprosy Management Information System in China for a descriptive analyses. Results: The leprosy incidence decreased from 0.13/10⁵ in 2010 to 0.06/10⁵ in 2020, and the average annual decline rate was 7.1%. A total of 499 leprosy cases newly detected were reported in Guangxi from 2010 to 2020, including 333 (66.7%) males, 166 (33.3%) females, 12 (2.4%) children, and 98 (19.6%) cases with grade 2 disabilities. The average age of the cases was 44.16±16.87. The mean delay period of new cases was 27 months, and the rate of early detection was 31.9%. 69.5% of the cases were detected through the examination at dermatology clinics, and 8.8% cases were found through detection on contacts, 27.3% of the  cases had a history of household contact. Leprosy cases were reported in all the prefectures of Guangxi, the new cases detected in Baise, Hechi and Chongzuo accounting for 51.9%. Conclusion: The number of newly detected leprosy cases reduced annually in Guangxi from 2010 to 2020, but efforts in early detection of new cases, such as contact examination and the training for dermatologist, should be strengthened to avoid delayed diagnosis.

Key words: leprosy, newly detected case, epidemiological characteristics