China Journal of Leprosy and Skin Diseases ›› 2023, Vol. 39 ›› Issue (11): 845-850.doi: 10.12144/zgmfskin202311845

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Update of the immunological research of psoriasis relapse

WANG Wenqiu1,2, WANG Rui2, LI Chengxin2   

  1. 1 Medical School of PLA, Beijing 100853, China; 2 Department of Dermatology, the 1th Medical Center, Chinese PLA General Hospital, Beijing 100853, China
  • Online:2023-11-15 Published:2023-10-27

Abstract: The mechanism of psoriasis recurrence is still unclear. Some studies have shown that skin tissue-resident memory T cells (TRM) play an important role in the recurrence of psoriasis. In addition, keratinocytes (KCs), γδT cells and dendritic cells (DCs) are also involved in disease recurrence to a certain extent. This paper reviews the latest immunological research progress of TRM involved in the recurrence of psoriasis, as well as the role of other cells in the recurrence in recent years, so as to provide ideas for the study of the recurrence mechanism of psoriasis.

Key words: psoriasis, relapse, tissue-resident memory T cells