China Journal of Leprosy and Skin Diseases ›› 2024, Vol. 40 ›› Issue (9): 669-673.doi: 10.12144/zgmfskin202409669

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Update of biologics and small molecule targeted drugs for the treatment of palmoplantar pustulosis

YANG Yannan, WANG Junhui   

  1. Department of Dermatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
  • Online:2024-09-15 Published:2024-08-14

Abstract: Palmoplantar pustulosis (PPP) is a chronic recurrent disease confined to the palmoplantar region, and there is no uniform standard of treatment. Targeted drugs and emerging drugs have been carried out in several clinical trials and case series studies. This paper reviews the progress of clinical research on PPP-related biologics and small molecule targeted drugs to provide a reference for further clinical treatment and related drug development.

Key words: biological agents, small molecule drugs, palmoplantar pustulosis, clinical trials, case series studies