China Journal of Leprosy and Skin Diseases ›› 2025, Vol. 41 ›› Issue (8): 620-625.doi: 10.12144/zgmfskin202508620

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Pathogenesis of tinea capitis from the multidimensional perspective of dermatophytes-host-microecology

WU Dandan1,2, ZHU Qingying1,2, YIN Bin2   

  1. 1 Graduate School of North Sichuan Medical College, Nanchong 637000, China; 2 Department of Dermatology, Chengdu Second People's Hospital, Chengdu 610017, China
  • Online:2025-08-15 Published:2025-08-01

Abstract: Tinea capitis is a superficial fungal infection of the hair and scalp caused by dermatophytes, which is more common in children and postmenopausal women. The pathogenesis of tinea capitis involves the invasion mechanism of dermatophytes, the interaction between dermatophytes and host immunity, and the influence of scalp microecological imbalance, especially the change of sebaceous gland function and microbial community disorder on the occurrence and development of tinea capitis. This paper review the pathogenesis of tinea capitis from various aspects, and provide scientific basis for the development of new prevention and treatment strategies.

Key words: tinea capitis, dermatophytes, immune response, scalp microecology, pathogenesis