China Journal of Leprosy and Skin Diseases ›› 2023, Vol. 39 ›› Issue (4): 236-241.doi: 10.12144/zgmfskin202304236

• Original Articles • Previous Articles     Next Articles

Five cases of infant kerion celsi successfully treated with oral itraconazole solution and literature review

ZHANG Muqiu1,2, ZHUANG Kaiwen1, RAN Xin1, ZHOU Yike1,2, Sushmita Pradhan1, RAN Yuping1   

  1. 1 Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu 610041, China;
    2 West China Hospital, West China School Medicine, Sichuan University, Chengdu 610041, China
  • Online:2023-04-15 Published:2023-03-27

Abstract: We report 5 cases of infant kerion celsi treated with itraconazole oral solution and review the related literature. The 5 cases were aged from 2 to 12 months, clinical manifestations included scalp erythema, scales, abscess and alopecia. The diagnosis was based on the dermascopy characteristics of the damaged hair, the fungal spores and/or hyphae confirmend under the fluorescence microscope after the calcium fluorescence white staining of the diseased hairs. The 5 cases were all cured with itraconazole solution at a dosage of 5 mg/kg·d, and the treatment courses varied from 3 to 12 weeks. Only one patient had mild transient diarrhea during the treatment process, and gradually relieved without medication withdrawal. The characteristics and efficacy of itraconazole in treating infantile tinea capitis from the 7 cases reported in the literature were analyzed. The conclusion of itraconazole oral solution is convenient, safe, effective and well tolerated in treating infantile tinea capitis.

Key words: infant, tinea capitis, kerion celsi, dermoscopy, calcium fluorescent microscopy, itraconazole oral solution