Abstract: Sweet syndrome (SS) is an inflammatory neutrophilic dermatosis of unknown etiology, which is associated with infections, drugs, tumors and autoimmune diseases. The pathogenesis involves neutrophil dysfunction, immune imbalance and genetic factors. Traditional first-line treatment is preferred to the systematic application of glucocorticoids. In recent years, as the research of SS has made some progress, biologics and small molecule targeted drugs have also been reported to treat SS successfully. The pathogenesis and therapeutic progress of SS are reviewed in this paper.

Key words: Sweet syndrome, acute febrile neutrophilic dermatosis, pathogenesis, therapy