中国麻风皮肤病杂志 ›› 2020, Vol. 36 ›› Issue (7): 407-409.doi: 10.12144/zgmfskin202007407

• 论著 • 上一篇    下一篇

87例妊娠梅毒患者临床特征和妊娠结局的回顾性分析

朱海军,吉向丽,李芳芳,伍婕,王文鑫   

  1. 赤峰市医院，赤峰，024000
  • 出版日期:2020-07-02 发布日期:2020-07-02
  • 通讯作者: 王文鑫，E-mail: Wangwenxin1974@163.com

Retrospective analysis of pregnancy outcomes of 87 patients with pregnancy syphilis

ZHU Haijun, JI Xiangli, LI Fangfang, WU Jie, WANG Wenxin   

  1. Chifeng Municipal Hospital, Chifeng 024000, China
  • Online:2020-07-02 Published:2020-07-02
  • Contact: WANG Wenxin, E-mail: Wangwenxin1974@163.com

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摘要： 对我院2015年1月1日至2018年12月31日诊治的87例妊娠梅毒患者的临床资料进行回顾性分析，结果示潜伏梅毒80例，一期梅毒和二期梅毒患者分别为4例和3例。潜伏梅毒患者中RPR滴度≤1:4者59例，≥1:8者21例。一期梅毒和二期梅毒患者中RPR滴度≤1:4者1例，≥1:8者6例；87例患者中，72例（82.76%）在孕期进行了抗梅毒治疗。妊娠梅毒患者的不良妊娠结局发生率为23.53%，其中先天梅毒的发生率为3.80%。RPR滴度、梅毒诊断孕周及治疗情况与不良妊娠结局的发生相关(均P＜0.05)。

关键词: 妊娠, 梅毒

Abstract: The data of 87 pregnant syphilis patients in our hospital diagnosed from January 1st, 2015 to December 31, 2018 was analyzed retrospectively. Of 87 patients, 80 were latent syphilis, 4 were pristmary syphilis, and 3 were secondary syphilis. Of 80 latent syphilis patients, the RPR titer was ≤1:4 in 59 patients, ≥1:8 in 21. Of the 7 primary syphilis and secondary syphilis patients, the RPR titer was ≤1:4 in one patient and ≥1:8 in 6 patients. Of 87 patients, 72 (82.76%) patients were treated during pregnancy. The occurence adverse pregnancy outcomes was 23.53%, of which congenital syphilis accunted for 3.80%. The serum RPR titer, gestational weeks at the time of syphilis diagnosis, and treatment were associated with the adverse pregnancy outcome (Ps<0.05). 

Key words: pregnancy, syphilis