Abstract: Objective: To detect drug resistance of patients with gonorrhea. Methods: The patients with gonorrhoea were collected from September 2016 to December 2018. The minimum inhibitory concentrations (MICs) were determined by E-test for penicillin, tetracycline, ciprofloxacin, meleumycin, ceftriaxone, cefixime and azithromycin. Results: Eighty eight patients were collected, including 77 males and 11 females. The drug sensitivities were 97.73% (86 cases) for ciprofloxacin, 71.59% (63) for penicillin, 61.36% (54) for tetracycline resistance, 19.32% (17) for azithromycin, 1.14% (1) for cefixime, respectively, (and no patient resistance to meleumycin and ceftriaxone. Conclusion: Meleumycin, cepixime and ceftriaxone are still the first choice in the treatment of gonorrhea.

Key words: gonorrhea, clinical characteristics, drug resistance