Abstract: The data of the patients diagnosed as autoimmune blistering disease complicated with psoriasis in our hospital from January 2011 to September 2021 was analyzed retrospectively.  Twenty patients with autoimmune blistering disease complicated with psoriasis were collected, including 14 males and 6 females. The median age was (64.75±13.13) year. There were 17 patients who had developed psoriasis before autoimmune bullous disease with an average duration of (18.03±14.69) years. All patients were treated with systemic corticosteroids and/or immunosuppressive agents. No new blister lesions occurred and psoriatic lesions remained stable in 15 patients. Four cases were lost follow-up and one died. Autoimmune blistering disease complicated with psoriasis was rare, and the coexistence of two diseases should be noted.

Key words: autoimmune blistering disease, psoriasis, clinical analysis