China Journal of Leprosy and Skin Diseases ›› 2016, Vol. 32 ›› Issue (3): 189-191.

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Update of the oxidative stress in the pathogenesis of vitiligo

ZHAO Xiaofei, LIU Guoyan   

  1. Weifang Medical College,Weifang,Shandong 261000, China
  • Online:2016-03-15 Published:2018-12-19
  • Contact: LIU Guoyan, E-mail: wfliuguoyan@126.com

Abstract: Pathogenesis of vitiligo is complex, involving genetic, immunity, oxidative stress, apoptosis of functional melanocytes and (or) loss and neurohormonal hypothesis, etc. Keap1/Nrf2/ARE pathway associated with oxidative stress was reviewed in this paper.

Key words: vitiligo, oxidative stress, Keap1/Nrf2/ARE signal pathway