China Journal of Leprosy and Skin Diseases ›› 2016, Vol. 32 ›› Issue (6): 331-334.

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Meta-analysis of the efficacy of the auto-verruca implantation in the treatment of condyloma acuminatum

QIN Wei1, QUE Dong-mei 2, ZHANG Hao 3   

  1. 1. Department of Dermatology, Jiangmen Central Hospital, Jiangmen, Guangdong 529030,China; 2. Department of Dermatology, Affiliated Chen Xing-hai Hospital of Guangdong Medical College, Zhongshan, Guangdong 528415, China; 3. School of Public Health, Wuhan University, Wuhan, Hubei 430071, China
  • Online:2016-06-15 Published:2018-12-26
  • Contact: MinZhongsheng, E-mail: 82941853@qq.com

Abstract: Objective: To assess the efficacy of the auto-verruca implantation in the treatment of condyloma acuminatum. Methods:Clinical randomized controlled trials about auto-verruca implantation for treating condyloma acuminatum were searched in Pubmed, China Academic Journal Network Publishing Database, WanFang Data and China Science and Technology Database. The Meta-analysis was performed by Review Manager 5.3.5 software. Results:A total of 10 researches were included, with small bias and no heterogeneous (P=0.25). The result of Meta-analysis showed that the cure rate in the group of auto-verruca implantation combined CO2 laser was significantly higher than that in the group of CO2 laser alone, with a significant difference(Z=9.54,P<0.00001, RR=1.50,95%CI (1.38-1.63)). Conclusion:Combination of auto-verruca implantation and CO2 laser was more effective than CO2 alone in the treatment of condyloma acuminatum.

Key words: auto-verruca implantation, condyloma acuminatum, meta-analysis