中国麻风皮肤病杂志 ›› 2016, Vol. 32 ›› Issue (6): 331-334.

• 论著 • 上一篇    下一篇

自体疣包埋治疗尖锐湿疣疗效的Meta分析

覃巍1，阙冬梅2，张皓3   

  1. 1.江门市中心医院皮肤科，广东 江门，529030 2. 广东医学院附属陈星海医院皮肤科，广东 中山，528415 3. 武汉大学公共卫生学院，湖北 武汉，430071
  • 出版日期:2016-06-15 发布日期:2018-12-26
  • 通讯作者: 覃巍， E-mail: 82941853@qq.com

Meta-analysis of the efficacy of the auto-verruca implantation in the treatment of condyloma acuminatum

QIN Wei1, QUE Dong-mei 2, ZHANG Hao 3   

  1. 1. Department of Dermatology, Jiangmen Central Hospital, Jiangmen, Guangdong 529030，China; 2. Department of Dermatology, Affiliated Chen Xing-hai Hospital of Guangdong Medical College, Zhongshan, Guangdong 528415, China; 3. School of Public Health, Wuhan University, Wuhan, Hubei 430071, China
  • Online:2016-06-15 Published:2018-12-26
  • Contact: MinZhongsheng, E-mail: 82941853@qq.com

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摘要： 目的：评价自体疣包埋对尖锐湿疣的治疗效果。方法：在Pubmed、《中国学术期刊网络出版总库》、《万方数据库》、《中文科技期刊数据库》中检索符合标准的关于自体疣包埋治疗尖锐湿疣的随机对照试验，应用Review Manager 5.3.5软件进行Meta分析。结果：共纳入10篇文献，入选文献发表偏倚较小，无明显异质性（P=0.25）。Meta分析结果显示，自体疣包埋联合CO2激光治疗对尖锐湿疣的治愈率显著高于单用CO2激光治疗，差异有统计学意义[Z=9.54，P<0.00001, RR=1.50，95%CI (1.38-1.63)]。结论：自体疣包埋联合CO2激光治疗治疗尖锐湿疣疗效优于单用CO2激光治疗。

关键词: 自体疣包埋, 尖锐湿疣, Meta分析

Abstract: Objective: To assess the efficacy of the auto-verruca implantation in the treatment of condyloma acuminatum. Methods：Clinical randomized controlled trials about auto-verruca implantation for treating condyloma acuminatum were searched in Pubmed, China Academic Journal Network Publishing Database, WanFang Data and China Science and Technology Database. The Meta-analysis was performed by Review Manager 5.3.5 software. Results：A total of 10 researches were included, with small bias and no heterogeneous (P=0.25). The result of Meta-analysis showed that the cure rate in the group of auto-verruca implantation combined CO2 laser was significantly higher than that in the group of CO2 laser alone, with a significant difference（Z=9.54，P<0.00001, RR=1.50，95%CI (1.38-1.63)）. Conclusion：Combination of auto-verruca implantation and CO2 laser was more effective than CO2 alone in the treatment of condyloma acuminatum.

Key words: auto-verruca implantation, condyloma acuminatum, meta-analysis