Abstract: Pustular psoriasis is a severe subtype of psoriasis which is difficult to treat and life-threatening. Current treatments mainly include systematic use of acitretin, cyclosporine and methotrexate, as well as PUVA and topical treatment. But, some patients are resistant to treatment. Recently,  biologicals for the treatment of pustular psoriasis have been reported and   Those reports are  reviewed in the paper.

Key words: psoriasis, biologics, pustular psoriasis