China Journal of Leprosy and Skin Diseases ›› 2016, Vol. 32 ›› Issue (8): 468-470.

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Bullous systemic lupus erythematosus: a case report

YAN Tianmeng1, ZUO Yagang1, ZHANG Shu1, LIN Lan2, LIU Yuehua1, LI Li1, ZHANG Tao1, LAI Yamin3.   

  1. 1.Department of Dermatology, Peking Union Medical College Hospital,Beijing 100730,China; 2. College of life science and biotechnology, Shenyang Pharmaceutical University, Shenyang 110016,China; 3. Department of rheumatology, Peking Union Medical College Hospital,Beijing 100730,China
  • Online:2016-08-15 Published:2018-12-27
  • Contact: ZUO Yagang, E-mail: zuoyagang@263.net

Abstract: A 27-years-old female patient presented with cough for 4 months and erythema, vesicle and hair-loss for 2 months. Physical examination revealed sparse hair on the scalp, erythema on the face and finger pulp, bullas on the trunk and extremities. The bullas were negative in Nikolsky`s sign. Red blood cells and hemoglobin declined and anti-nuclear antibody, anti-dsDNA, antibody to type VII collagen in peripheral blood were positive. ANA, anti-dsDNA, anti-SSA, anti-SSB, anti-histone, anti-Ro 52 and anti-nucleosome antibodies in blister fluids were positive. The diagnosis of bullous systemic lupus erythematosus was made.

Key words: systemic lupus erythematosus, bullous, blister fluids