Abstract: Cutaneous squamous cell carcinoma (cSCC) is a common skin tumor in middle-aged and elderly people. Surgery is still the preferred treatment for cSCC, but considering the anatomical location, number of lesions, and the rate of recurrence after surgical resection, surgery is not suitable for all cSCC patients. Other treatment methods, such as photodynamic therapy, cryotherapy, radiotherapy, topical drugs and targeted drugs, can be used according to the specific situation to achieve individualized treatment. The update of treatment of cutaneous squamous cell carcinoma was reviewed in this paper.

Key words: cutaneous squamous cell carcinoma, treatment